A cross-kingdom interactome predicted by AlphaFold3 reveals a DNF2-centered interface required for symbiotic accommodation
This study utilizes AlphaFold3 to construct a cross-kingdom interactome between *Medicago truncatula* and *Sinorhizobium meliloti*, identifying a DNF2-centered molecular framework involving specific rhizobial proteins that is essential for maintaining symbiotic accommodation and nitrogen fixation in root nodules.